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Naho Takamiya's first day of her sophomore year of high school is off to an uneasy start. After waking up late, she receives a strange letter addressed to her. However, the letter is from herself—10 years in the future! At first, Naho is skeptical of the note; yet, after witnessing several events described to take place, she realizes the letter really is from her 26-year-old self. The note details that Naho's future life is filled with regrets, and she hopes that her younger self can correct the mistakes that were made in the past. The letter also warns her to keep a close eye on the new transfer student, Kakeru Naruse. Naho must be especially careful in making decisions involving him, as Kakeru is not around in the future. With the letter as her guide, Naho now has the power to protect Kakeru before she comes to regret it once more. [Written by MAL Rewrite]

When a young boy named Tooichi stumbles upon an old lamp in his grandfather's shed, he mistakes it for a toy and takes it outside to play. When his grandfather discovers this, he reprimands the boy and begins recounting the story behind the artifact—of how a small, traditional Japanese town became Westernized. In his youth, Tooichi's grandfather, Minosuke, made a living by doing errands and chores for the townspeople. After one errand takes him to a nearby town, he witnesses Western lamps—a technology unfamiliar to him—light up the streets, igniting a spark in the young boy. From that moment on, lamps became Minosuke's passion and profession, changing his and the townspeople's lives forever. [Written by MAL Rewrite]

In the second season the story continues exactly where it left off previously. Professor Itsuki's Fermentation Cellar and laboratory is ready for operation and with Sawaki Tadayasu's unique gift to see and communicate with microbes to help, Itsuki's motley group of students begin to process different fermented products like soy sauce and sake. (Source: ANN)

One could say that freshman college student Tadayasu Sawaki has a wide range of vision. He has a peculiar ability that allows him to see microorganisms with the naked eye. Sawaki can see all sorts of microbes, from the fungi that cause athlete's foot to the yeast used to make alcohol, with him perceiving his little friends as cute chibi creatures. Attending an agricultural university, his talent piques the interest of numerous professors, including Professor Itsuki, who specializes in fermentation. Sawaki starts school indifferent toward his ability, choosing an agricultural school in Tokyo. However, with the help of the eccentric community around him, he slowly learns to appreciate these visible microbes and his talent. The whimsical cast of professors and classmates attending the university almost makes Sawaki seem normal despite his ability. [Written by MAL Rewrite]